• Most Topular Stories

  • Respiration phase-locks to fast stimulus presentations: Implications for the interpretation of posterior midline “deactivations”

    Human Brain Mapping
    Willem Huijbers, Cyriel M.A. Pennartz, Ewa Beldzik, Aleksandra Domagalik, M. Vinck, Winnie F. Hofman, Roberto Cabeza, Sander M. Daselaar
    15 Apr 2014 | 11:52 pm
    Abstract The posterior midline region (PMR)—considered a core of the default mode network—is deactivated during successful performance in different cognitive tasks. The extent of PMR-deactivations is correlated with task-demands and associated with successful performance in various cognitive domains. In the domain of episodic memory, functional MRI (fMRI) studies found that PMR-deactivations reliably predict learning (successful encoding). Yet it is unclear what explains this relation. One intriguing possibility is that PMR-deactivations are partially mediated by respiratory artifacts.
  • Liver volume most common reason for donor exclusion

    Health Imaging - Health Imaging is a leading news website that reflects the clinical, informatics and practice management considerations involved with medical imaging.
    Evan Godt
    15 Apr 2014 | 4:26 pm
    A study of imaging findings in potential liver donors found that anatomic variations are common and many of these variations can exclude a potential donor, according to findings published in the April issue of the American Journal of Roentgenology.
  • Patient satisfaction improved by shared decision making during radiation therapy

    Radiology / Nuclear Medicine News From Medical News Today
    17 Apr 2014 | 12:00 am
    Playing an active role in their radiation treatment decisions leaves cancer patients feeling more satisfied with their care, and may even relieve psychological distress around the experience...
  • OncoBriefs: Chemo for Bladder Cancer, Myeloma Care (CME/CE)

    MedPage Today Radiology
    17 Apr 2014 | 1:12 pm
    (MedPage Today) -- The vast majority of patients with muscle-invasive bladder cancer do not receive chemotherapy, despite evidence of a significant survival benefit, investigators concluded after a 2,000-case review.
  • The Pitfalls of Giving Free Advice to Family and Friends

    Medscape Radiology Headlines
    10 Apr 2014 | 6:50 am
    As a doctor, giving medical advice is almost reflexive. But when family and friends expect a free medical opinion for every rash and bruise, is it wise to oblige? Here are the traps to watch for. Medscape Business of Medicine
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    American Journal of Neuroradiology current issue

  • Spontaneous Lateral Sphenoid Cephaloceles: Anatomic Factors Contributing to Pathogenesis and Proposed Classification [EDITOR'S CHOICE]

    Settecase, F., Harnsberger, H. R., Michel, M. A., Chapman, P., Glastonbury, C. M.
    10 Apr 2014 | 8:02 am
    SUMMARY: Spontaneous lateral sphenoid cephaloceles arise from bony defects in the lateral sphenoid, in the absence of predisposing factors such as trauma, surgery, mass, or congenital skull base malformation. We reviewed CT and MR imaging findings and clinical data of 26 patients with spontaneous lateral sphenoid cephaloceles to better understand anatomic contributions to pathogenesis, varying clinical and imaging manifestations, and descriptive terminology. Two types of spontaneous lateral sphenoid cephaloceles were identified. In 15 of 26 patients, a type 1 spontaneous lateral sphenoid…
  • MR Imaging Evaluation of Inferior Olivary Nuclei: Comparison of Postoperative Subjects with and without Posterior Fossa Syndrome [PEDIATRICS]

    Patay, Z., Enterkin, J., Harreld, J. H., Yuan, Y., Lobel, U., Rumboldt, Z., Khan, R., Boop, F.
    10 Apr 2014 | 8:02 am
    BACKGROUND AND PURPOSE: Posterior fossa syndrome is a severe postoperative complication occurring in up to 29% of children undergoing posterior fossa tumor resection; it is most likely caused by bilateral damage to the proximal efferent cerebellar pathways, whose fibers contribute to the Guillain-Mollaret triangle. When the triangle is disrupted, hypertrophic olivary degeneration develops. We hypothesized that MR imaging patterns of inferior olivary nucleus changes reflect patterns of damage to the proximal efferent cerebellar pathways and show association with clinical findings, in…
  • Diffusion Imaging for Tumor Grading of Supratentorial Brain Tumors in the First Year of Life [PEDIATRICS]

    Kralik, S. F., Taha, A., Kamer, A. P., Cardinal, J. S., Seltman, T. A., Ho, C. Y.
    10 Apr 2014 | 8:02 am
    BACKGROUND AND PURPOSE: Supratentorial tumors in the first year of life are typically large and heterogeneous at presentation, making differentiation of these CNS neoplasms on pre-operative imaging difficult. We hypothesize that the ADC value can reliably differentiate high- versus low-grade supratentorial tumors in this patient population. MATERIALS AND METHODS: A blinded review of ADC maps was performed on 19 patients with histologically proved supratentorial brain tumors diagnosed within the first year of life. Minimum ADC values obtained by region of interest from 2 neuroradiologists were…
  • Time-Dependent Structural Changes of the Dentatothalamic Pathway in Children Treated for Posterior Fossa Tumor [PEDIATRICS]

    Perreault, S., Lober, R. M., Cheshier, S., Partap, S., Edwards, M. S., Yeom, K. W.
    10 Apr 2014 | 8:02 am
    BACKGROUND AND PURPOSE: Injury to the dentatothalamic pathway that originates in the cerebellum has been suggested as a mechanism for neurologic complications in children treated for posterior fossa tumors. We hypothesized that time-dependent changes occur in the dentatothalamic pathway. MATERIALS AND METHODS: Diffusion tensor evaluation was performed in 14 children (median age, 4.1 years; age range, 1–20 years) who underwent serial MR imaging at 3T as part of routine follow-up after posterior fossa tumor resection with or without adjuvant therapy. Tensor metrics were obtained in the…
  • Diffusional Kurtosis Imaging of the Developing Brain [PEDIATRICS]

    Paydar, A., Fieremans, E., Nwankwo, J. I., Lazar, M., Sheth, H. D., Adisetiyo, V., Helpern, J. A., Jensen, J. H., Milla, S. S.
    10 Apr 2014 | 8:02 am
    BACKGROUND AND PURPOSE: Diffusional kurtosis imaging is an extension of DTI but includes non-Gaussian diffusion effects, allowing more comprehensive characterization of microstructural changes during brain development. Our purpose was to use diffusional kurtosis imaging to measure age-related microstructural changes in both the WM and GM of the developing human brain. MATERIALS AND METHODS: Diffusional kurtosis imaging was performed in 59 subjects ranging from birth to 4 years 7 months of age. Diffusion metrics, fractional anisotropy, and mean kurtosis were collected from VOIs within multiple…
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    Journal of Medical Imaging and Radiation Oncology

  • Radiotherapy in fascial fibromatosis: A case series, literature review and considerations for treatment of early-stage disease

    Solveig Grenfell, Martin Borg
    14 Apr 2014 | 8:34 pm
    Abstract IntroductionPalmar and plantar fascial fibromatoses are benign hyperproliferative disorders of the deep fascia of the palm and sole. This study seeks to examine the role of radiotherapy in the management of fascial fibromatosis. MethodSix consecutive cases of early-stage fascial fibromatosis treated with radiotherapy at the Adelaide Radiotherapy Centre between July 2008 and May 2011 were analysed. The results of the case series were compared with a systematic review of the literature. ResultsAll six cases regressed or showed a reduction of symptoms following radiotherapy. Treatment…
  • Bone complications after pelvic radiation therapy: Evaluation with MRI

    Gamze Ugurluer, Tugana Akbas, Taner Arpaci, Nazli Ozcan, Meltem Serin
    9 Apr 2014 | 3:58 am
    Abstract IntroductionThe purpose of this study was to assess the incidence, distribution and MRI characteristics of pelvic bone complications after radiation therapy. MethodsThe medical charts of 345 patients who received pelvic radiation therapy were retrospectively reviewed. A total of 122 patients, 99 women and 23 men, with a mean age of 57 (range 32–87 years) were included in this study. The MR images were retrospectively reviewed by two radiologists. ResultsFatty replacement of bone marrow was seen in all patients. Pelvic bone complications and focal red marrow changes were identified…
  • External evaluation of the Radiation Therapy Oncology Group brachial plexus contouring protocol: Several issues identified

    Myo Min, Daniel Roos, Elly Keating, Michael Penniment, Scott Carruthers, Lydia Zanchetta, Karen Wong, John Shakeshaft, Siddhartha Baxi
    9 Apr 2014 | 3:39 am
    Abstract IntroductionThe aims of the study were to evaluate interobserver variability in contouring the brachial plexus (BP) using the Radiation Therapy Oncology Group (RTOG)-approved protocol and to analyse BP dosimetries. MethodsSeven outliners independently contoured the BPs of 15 consecutive patients. Interobserver variability was reviewed qualitatively (visually by using planning axial computed-tomography images and anteroposterior digitally reconstructed radiographs) and quantitatively (by volumetric and statistical analyses). Dose–volume histograms of BPs were calculated and…
  • Continuing Professional Development

    1 Apr 2014 | 6:35 pm
  • Utility of hCRH-stimulated (18) F-FDG PET-CT scan in localisation of pituitary microadenoma in Cushing's disease

    HP Patt, V Lele, A Lila, T Bandgar, N Shah
    1 Apr 2014 | 6:35 pm
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    BMC Medical Imaging - Latest Articles

  • Assessment of the level of agreement in the interpretation of plain radiographs of lumbar spondylosis among clinical physiotherapists in Ghana

    Ajediran Bello
    28 Mar 2014 | 5:00 pm
    Background: Objective physical assessment of patients with lumbar spondylosis involves plain film radiographs (PFR) viewing and interpretation by the radiologists. Physiotherapists also routinely assess PFR within the scope of their practice. However, studies appraising the level of agreement of physiotherapists’ PFR interpretation with radiologists are not common in Ghana.MethodForty-one (41) physiotherapists took part in the cross-sectional survey. An assessment guide was developed from findings of the interpretation of three PFR of patients with lumbar spondylosis by a radiologist. The…
  • Animal study assessing safety of an acoustic coupling fluid that holds the potential to avoid surgically induced artifacts in 3D ultrasound guided operations

    Asgeir Jakola
    24 Mar 2014 | 5:00 pm
    Background: Use of ultrasound in brain tumor surgery is common. The difference in attenuation between brain and isotonic saline may cause artifacts that degrade the ultrasound images, potentially affecting resection grades and safety. Our research group has developed an acoustic coupling fluid that attenuates ultrasound energy like the normal brain. We aimed to test in animals if the newly developed acoustic coupling fluid may have harmful effects. Methods: Eight rats were included for intraparenchymal injection into the brain, and if no adverse reactions were detected, 6 pigs were to be…
  • Mammographic images segmentation based on chaotic map clustering algorithm

    Marius Iacomi
    24 Mar 2014 | 5:00 pm
    Background: This work investigates the applicability of a novel clustering approach to the segmentation of mammographic digital images. The chaotic map clustering algorithm is used to group together similar subsets of image pixels resulting in a medically meaningful partition of the mammography. Methods: The image is divided into pixels subsets characterized by a set of conveniently chosen features and each of the corresponding points in the feature space is associated to a map. A mutual coupling strength between the maps depending on the associated distance between feature space points is…
  • The diagnostic validity of musculoskeletal ultrasound in lateral epicondylalgia: a systematic review

    Valentin Dones
    2 Mar 2014 | 4:00 pm
    Background: Ultrasound is considered a reliable, widely available, non-invasive and inexpensive imaging technique for assessing soft tissue involvement in Lateral epicondylalgia. Despite the number of diagnostic studies for Lateral Epicondylalgia, there is no consensus in the current literature on the best abnormal ultrasound findings that confirm lateral epicondylalgia. Methods: Eligible studies identified by searching electronic databases, scanning reference lists of articles and chapters on ultrasound in reference books, and consultation of experts in sonography. Three reviewers (VCDIII,…
  • Intelligent neonatal monitoring based on a virtual thermal sensor

    Abbas Abbas
    1 Mar 2014 | 4:00 pm
    Background: Temperature measurement is a vital part of daily neonatal care. Accurate measurements are important for detecting deviations from normal values for both optimal incubator and radiant warmer functioning. The purpose of monitoring the temperature is to maintain the infant in a thermoneutral environmental zone. This physiological zone is defined as the narrow range of environmental temperatures in which the infant maintains a normal body temperature without increasing his or her metabolic rate and thus oxygen consumption. Although the temperature measurement gold standard is the skin…
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    Cardiovascular Ultrasound - Latest Articles

  • Arterial stiffness in adult patients after Fontan procedure

    Lidia Tomkiewicz-Pajak
    9 Apr 2014 | 5:00 pm
    ObjectivesIncreased arterial stiffness is a risk factor of atherosclerosis and cardio-vascular complications. The aim of the study was to determine whether peripheral vascular function might be an early marker of impaired health status in patients with a single ventricle after Fontan procedure.Methods and resultsTwenty five consecutive adults (11 women and 14 men) aged 24.7 ± 6.2 years after the Fontan procedure and 25 sex, age and BMI match healthy volunteers underwent physical examination, blood analysis, transthoracic echocardiography and noninvasive assessment of aortic stiffness.
  • Predictors and prognosis of early ischemic mitral regurgitation in the era of primary percutaneous coronary revascularisation

    Jimmy MacHaalany
    2 Apr 2014 | 5:00 pm
    Background: Studies assessing ischemic mitral regurgitation (IMR) comprised of heterogeneous population and evaluated IMR in the subacute setting. The incidence of early IMR in the setting of primary PCI, its progression and clinical impact over time is still undetermined. We sought to determine the predictors and prognosis of early IMR after primary percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction (STEMI). Methods: Using our primary PCI database, we screened for patients who underwent ≥2 transthoracic echocardiograms early (1–3 days) and late (1 year)…
  • Echocardiographic follow-up of patients with systemic sclerosis by 2D speckle tracking echocardiography of the left ventricle

    Sebastian Spethmann
    28 Mar 2014 | 5:00 pm
    Background: Subclinical myocardial involvement is common in systemic sclerosis (SSc) and associated with poor prognosis. Early detection, particularly during follow-up, is important. Two-dimensional speckle tracking echocardiography (STE) has already been shown to detect early left ventricular systolic impairment in SSc patients with advanced disease. The aim of this study was to assess the ability of STE to diagnose changes in left ventricular function in patients with SSc with preserved LV ejection fraction (LVEF) and normal pulmonary pressure over time. Methods: This single-center pilot…
  • Coronary artery occlusions diagnosed by transthoracic Doppler

    Johnny Vegsundvåg
    14 Mar 2014 | 5:00 pm
    Background: Our aim was to assess whether anterograde flow velocities in septal perforating branches could identify an occluded contralateral coronary artery, and to assess the feasibility and accuracy of diagnosing occlusions in the three main coronary arteries by the combined use of several noninvasive parameters indicating collateral flow. Methods: A total of 108 patients scheduled for coronary angiography because of chest pain or acute coronary syndromes were studied using transthoracic Doppler echocardiography. Results: Anterograde peak diastolic flow velocities (pDV) in septal…
  • Increased longitudinal contractility and diastolic function at rest in well-trained amateur Marathon runners: a speckle tracking echocardiography study

    Sebastian Schattke
    25 Feb 2014 | 4:00 pm
    Background: Regular physical activity reduces cardiovascular risk. There is concern that Marathon running might acutely damage the heart. It is unknown to what extent intensive physical endurance activity influences the cardiac mechanics at resting condition. Methods: Eighty-four amateur marathon runners (43 women and 41 men) from Berlin-Brandenburg area who had completed at least one marathon previously underwent clinical examination and echocardiography at least 10 days before the Berlin Marathon at rest. Standard transthoracic echocardiography and 2D strain and strain rate analysis were…
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    Journal of Vascular and Interventional Radiology - Articles in Press

  • Clinical Impact of Sacroplasty on Patient Mobility - Corrected Proof

    Jennifer Talmadge, Kahsi Smith, Thomas Dykes, Derek Mittleider
    6 Apr 2014 | 5:00 pm
    Abstract: Purpose: To evaluate the effect of sacroplasty on patient mobility and pain when performed as a treatment for sacral insufficiency fractures.Materials and Methods: Imaging with computed tomography (CT), magnetic resonance imaging, or bone scan confirmed the diagnosis of sacral insufficiency fractures. Baseline clinical mobility scale (CMS) score and visual analog scale (VAS) pain score were recorded. Sacroplasty was performed under CT guidance. Follow-up CMS and VAS scores were assessed at 4, 24, and 48 weeks.Results: Eighteen elderly patients (age 80 y ± 8.5; 17 women) were…
  • Role of C-Arm CT in Identifying Caudate Arteries Supplying Hepatocellular Carcinoma - Corrected Proof

    Won Seok Choi, Hyo-Cheol Kim, Saebeom Hur, Jin Woo Choi, Jeong-Hoon Lee, Su Jong Yu, Jin Wook Chung
    6 Apr 2014 | 5:00 pm
    Abstract: Purpose: To evaluate the role of C-arm computed tomography (CT) performed at the proper hepatic artery or equivalent in patients with caudate-lobe hepatocellular carcinoma (HCC) for the detection of tumor-feeding arteries during chemoembolization.Materials and Methods: From July 2009 to June 2012, 1,785 patients received initial chemoembolization at a single institution. Among them, 52 patients with caudate HCC underwent initial chemoembolization with the use of C-arm CT. C-arm CT images were obtained at the proper hepatic artery or equivalent. Two radiologists reviewed the C-arm CT…
  • Safety and Feasibility of Same-Day Discharge of Patients with Hepatocellular Carcinoma Treated with Transarterial Chemoembolization with Drug-Eluting Beads in a Liver Transplantation Program - Corrected Proof

    Felipe Nasser, Rafael N. Cavalcante, Francisco L. Galastri, Marcelo B. de Rezende, Guilherme G. Felga, Fabiellen B. Travassos, Bruna De Fina, Breno B. Affonso
    3 Apr 2014 | 5:00 pm
    abstract: Purpose: To evaluate the safety and feasibility of same-day discharge of patients with hepatocellular carcinoma (HCC) treated with transarterial chemoembolization with the use of drug-eluting beads (DEBs) and elucidate the prognostic factors for hospital admission.Materials and Methods: A total of 266 DEB chemoembolization procedures in 154 consecutive patients listed for liver transplantation or identified for potential HCC downstaging were performed with the outpatient treatment protocol. Endpoints evaluated were admission to the hospital after the procedure for clinical reasons,…
  • Predictors of Patency after Balloon Angioplasty in Hemodialysis Fistulas: A Systematic Review - Corrected Proof

    Brendon L. Neuen, Ronny Gunnarsson, Angela C. Webster, Richard A. Baer, Jonathan Golledge, Murty L. Mantha
    2 Apr 2014 | 5:00 pm
    Abstract: Percutaneous transluminal angioplasty (PTA) is an established treatment for dysfunctional hemodialysis fistulas. This article systematically reviews evidence for predictors of patency after PTA. Outcomes assessed were primary, assisted primary, and secondary patency after intervention, and findings were summarized descriptively. This review included 11 nonrandomized observational studies of 965 fistulas in 939 patients. Follow-up ranged from 0 days to 10 years. Study quality was overall suboptimal. Newer fistulas and longer lesion length may be associated with primary patency loss…
  • Radiofrequency Ablation of T1 Lung Carcinoma: Comparison of Outcomes for First Primary, Metachronous, and Synchronous Lung Tumors - Corrected Proof

    Carole A. Ridge, Mikhail Silk, Elena N. Petre, Joseph P. Erinjeri, William Alago, Robert J. Downey, Constantinos T. Sofocleous, Raymond H. Thornton, Stephen B. Solomon
    2 Apr 2014 | 5:00 pm
    Abstract: Purpose: To report and compare outcomes after radiofrequency ablation for treatment-naïve first primary, metachronous, and synchronous T1 lung tumors.Materials and Methods: This institutional review board–approved retrospective study reviewed 29 patients (12 men and 17 women; median age, 73 y; age range, 55–86 y) with treatment-naïve T1 lung tumors treated with radiofrequency ablation. Tumors in the 29 patients included 21 T1a and 8 T1b first primary (n = 11), metachronous (n = 14), or synchronous (n = 4) tumors (adenocarcinoma, n = 25; squamous cell carcinoma, n = 3;…
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    Human Brain Mapping

  • A hierarchical method for whole-brain connectivity-based parcellation

    David Moreno-Dominguez, Alfred Anwander, Thomas R. Knösche
    17 Apr 2014 | 3:22 am
    Abstract In modern neuroscience there is general agreement that brain function relies on networks and that connectivity is therefore of paramount importance for brain function. Accordingly, the delineation of functional brain areas on the basis of diffusion magnetic resonance imaging (dMRI) and tractography may lead to highly relevant brain maps. Existing methods typically aim to find a predefined number of areas and/or are limited to small regions of grey matter. However, it is in general not likely that a single parcellation dividing the brain into a finite number of areas is an adequate…
  • Alterations in amplitude of low frequency fluctuation in treatment-naïve major depressive disorder measured with resting-state fMRI

    Jie Liu, Ling Ren, Fay Y. Womer, Jue Wang, Guoguang Fan, Wenyan Jiang, Hilary P. Blumberg, Yanqing Tang, Ke Xu, Fei Wang
    17 Apr 2014 | 3:22 am
    Abstract There are limited resting-state functional magnetic resonance imaging (fMRI) studies in major depressive disorder (MDD). Of these studies, functional connectivity analyses are mostly used. However, a new method based on the magnitude of low frequency fluctuation (LFF) during resting-state fMRI may provide important insight into MDD. In this study, we examined the amplitude of LFF (ALFF) within the whole brain during resting-state fMRI in 30 treatment-naïve MDD subjects and 30 healthy control (HC) subjects. When compared with HC, MDD subjects showed increased ALFF in the frontal…
  • Respiration phase-locks to fast stimulus presentations: Implications for the interpretation of posterior midline “deactivations”

    Willem Huijbers, Cyriel M.A. Pennartz, Ewa Beldzik, Aleksandra Domagalik, M. Vinck, Winnie F. Hofman, Roberto Cabeza, Sander M. Daselaar
    15 Apr 2014 | 11:52 pm
    Abstract The posterior midline region (PMR)—considered a core of the default mode network—is deactivated during successful performance in different cognitive tasks. The extent of PMR-deactivations is correlated with task-demands and associated with successful performance in various cognitive domains. In the domain of episodic memory, functional MRI (fMRI) studies found that PMR-deactivations reliably predict learning (successful encoding). Yet it is unclear what explains this relation. One intriguing possibility is that PMR-deactivations are partially mediated by respiratory artifacts.
  • Early life trauma and directional brain connectivity within major depression

    Merida M. Grant, David White, Jennifer Hadley, Nathan Hutcheson, Richard Shelton, Karthik Sreenivasan, Gopikrishna Deshpande
    15 Apr 2014 | 5:35 am
    Abstract Objective: Early life trauma (ELT) is a significant risk factor for the onset of depression. Emerging findings indicate ELT is associated with enhanced amygdala reactivity to aversive stimuli in never-depressed healthy controls as well as those with acute depression but may be absent in non-ELT exposed depressed. The precise mechanism mediating these differences in amygdala reactivity remains unclear. Method: The authors used Granger causality methods to evaluate task-based directional connectivity between medial or lateral prefrontal cortex (PFC) and amygdala in 20 unmedicated…
  • Topological methods reveal high and low functioning neuro-phenotypes within fragile X syndrome

    David Romano, Monica Nicolau, Eve-Marie Quintin, Paul K. Mazaika, Amy A. Lightbody, Heather Cody Hazlett, Joseph Piven, Gunnar Carlsson, Allan L. Reiss
    15 Apr 2014 | 5:30 am
    Abstract Fragile X syndrome (FXS), due to mutations of the FMR1 gene, is the most common known inherited cause of developmental disability as well as the most common single-gene risk factor for autism. Our goal was to examine variation in brain structure in FXS with topological data analysis (TDA), and to assess how such variation is associated with measures of IQ and autism-related behaviors. To this end, we analyzed imaging and behavioral data from young boys (n = 52; aged 1.57–4.15 years) diagnosed with FXS. Application of topological methods to structural MRI data revealed two large…
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    International Journal of Radiation Oncology * Biology * Physics - Articles in Press

  • Phase 1 Pharmacogenetic and Pharmacodynamic Study of Sorafenib With Concurrent Radiation Therapy and Gemcitabine in Locally Advanced Unresectable Pancreatic Cancer - Corrected Proof

    E. Gabriela Chiorean, Bryan P. Schneider, Fatih M. Akisik, Susan M. Perkins, Stephen Anderson, Cynthia S. Johnson, John DeWitt, Paul Helft, Romnee Clark, Erica L. Johnston, A. John Spittler, Jill Deluca, Guixue Bu, Safi Shahda, Patrick J. Loehrer, Kumar Sandrasegaran, Higinia R. Cardenes
    13 Apr 2014 | 5:00 pm
    Purpose: To define the safety, efficacy, and pharmacogenetic and pharmacodynamic effects of sorafenib with gemcitabine-based chemoradiotherapy (CRT) in locally advanced pancreatic cancer.Methods and Materials: Patients received gemcitabine 1000 mg/m2 intravenously weekly × 3 every 4 weeks per cycle for 1 cycle before CRT and continued for up to 4 cycles after CRT. Weekly gemcitabine 600 mg/m2 intravenously was given during concurrent intensity modulated radiation therapy of 50 Gy to gross tumor volume in 25 fractions. Sorafenib was dosed orally 400 mg twice daily until progression,…
  • A Prospective Study of 18FDG-PET With CT Coregistration for Radiation Treatment Planning of Lymphomas and Other Hematologic Malignancies - Corrected Proof

    Stephanie A. Terezakis, Heiko Schöder, Alexander Kowalski, Patrick McCann, Remy Lim, Alla Turlakov, Mithat Gonen, Chris Barker, Anuj Goenka, Shona Lovie, Joachim Yahalom
    13 Apr 2014 | 5:00 pm
    Purpose: This prospective single-institution study examined the impact of positron emission tomography (PET) with the use of 2-[18F] fluoro-2-deoxyglucose and computed tomography (CT) scan radiation treatment planning (TP) on target volume definition in lymphoma.Methods and Materials: 118 patients underwent PET/CT TP during June 2007 to May 2009. Gross tumor volume (GTV) was contoured on CT-only and PET/CT studies by radiation oncologists (ROs) and nuclear medicine physicians (NMPs) for 95 patients with positive PET scans. Treatment plans and dose-volume histograms were generated for CT-only…
  • Quantification of Proton Dose Calculation Accuracy in the Lung - Corrected Proof

    Clemens Grassberger, Juliane Daartz, Stephen Dowdell, Thomas Ruggieri, Greg Sharp, Harald Paganetti
    13 Apr 2014 | 5:00 pm
    Purpose: To quantify the accuracy of a clinical proton treatment planning system (TPS) as well as Monte Carlo (MC)–based dose calculation through measurements and to assess the clinical impact in a cohort of patients with tumors located in the lung.Methods and Materials: A lung phantom and ion chamber array were used to measure the dose to a plane through a tumor embedded in the lung, and to determine the distal fall-off of the proton beam. Results were compared with TPS and MC calculations. Dose distributions in 19 patients (54 fields total) were simulated using MC and compared to the TPS…
  • Single-Fraction Proton Beam Stereotactic Radiosurgery for Cerebral Arteriovenous Malformations - Corrected Proof

    Jona A. Hattangadi-Gluth, Paul H. Chapman, Daniel Kim, Andrzej Niemierko, Marc R. Bussière, Alison Stringham, Juliane Daartz, Christopher Ogilvy, Jay S. Loeffler, Helen A. Shih
    13 Apr 2014 | 5:00 pm
    Purpose/Objective(s): To evaluate the obliteration rate and potential adverse effects of single-fraction proton beam stereotactic radiosurgery (PSRS) in patients with cerebral arteriovenous malformations (AVMs).Methods and Materials: From 1991 to 2010, 248 consecutive patients with 254 cerebral AVMs received single-fraction PSRS at our institution. The median AVM nidus volume was 3.5 cc (range, 0.1-28.1 cc), 23% of AVMs were in critical/deep locations (basal ganglia, thalamus, or brainstem), and the most common prescription dose was 15 Gy(relative biological effectiveness [RBE]).
  • Cost-Effectiveness Analysis of Intensity Modulated Radiation Therapy Versus 3-Dimensional Conformal Radiation Therapy for Anal Cancer - Corrected Proof

    Joseph C. Hodges, Muhammad S. Beg, Prajnan Das, Jeffrey Meyer
    9 Apr 2014 | 5:00 pm
    Purpose: To compare the cost-effectiveness of intensity modulated radiation therapy (IMRT) and 3-dimensional conformal radiation therapy (3D-CRT) for anal cancer and determine disease, patient, and treatment parameters that influence the result.Methods and Materials: A Markov decision model was designed with the various disease states for the base case of a 65-year-old patient with anal cancer treated with either IMRT or 3D-CRT and concurrent chemotherapy. Health states accounting for rates of local failure, colostomy failure, treatment breaks, patient prognosis, acute and late toxicities,…
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    Journal of Clinical Ultrasound

  • Fetal intracardiac rhabdomyoma in beckwith-wiedemann syndrome

    Ann Carolin Longardt, Andreas Nonnenmacher, Luitgard Graul-Neumann, Bernd Opgen-Rhein, Wolfgang Henrich, Christoph Bührer, Dieter Hüseman
    17 Apr 2014 | 11:24 pm
    ABSTRACT Fetal cardiac tumors are a rare finding in prenatal ultrasonography. Most of them are rhabdomyoma, which are thought to be pathognomonic for tuberous sclerosis complex. We present an infant with prenatally diagnosed cardiac rhabdomyoma (CR), who was found to suffer from Beckwith-Wiedemann syndrome (BWS). This congenital overgrowth syndrome is characterized by macrosomia, macroglossia, omphalocele, hypoglycemia, and hemihypertrophy. BWS patients have an increased risk for formation of benign and malignant tumors, typically intra-abdominally located, but, to the best of our knowledge,…
  • Evaluation of retrobulbar blood flow with color doppler ultrasonography in patients with central serous chorioretinopathy

    Cihad Hamidi, Fatih Mehmet Türkcü, Cemil Göya, Mehmet Güli Çetinçakmak, Harun Yüksel, Memik Teke, Salih Hattapoğlu, Aslan Bilici
    17 Apr 2014 | 11:22 pm
    ABSTRACT BackgroundTo compare retrobulbar blood flow in patients with central serous chorioretinopathy (CSC) and healthy subjects using color Doppler ultrasonography. MethodsThirty patients (age 23–54 years) with a first episode of acute CSC and 30 healthy controls (age 30–44 years) were evaluated. The peak systolic blood flow velocity, end-diastolic velocity (EDV), resistance index (RI), and pulsatility index (PI) were measured in the ophthalmic, posterior ciliary, and central retinal arteries. ResultsThe posterior ciliary and central retinal artery EDV were lower in the patient group…
  • Contrast-enhanced ultrasound characterization of renal mucinous tubular and spindle cell carcinoma: Report of two cases

    Lixia Yan, Beijian Huang, Liyun Xue, Qing Lu, Jiexian Wen, Wenping Wang
    5 Apr 2014 | 2:22 am
    ABSTRACT Mucinous tubular and spindle cell carcinoma of the kidney is a relatively rare pathologic entity that has recently been described in the World Health Organization 2004 renal cell carcinoma classification. We report two cases of mucinous tubular and spindle cell carcinoma in which contrast-enhanced ultrasound was used. © 2014 Wiley Periodicals, Inc. J Clin Ultrasound, 2014
  • Solitary osteochondroma of the distal radius: A rare cause of carpal tunnel syndrome diagnosed using ultrasound

    Torsten Franz, Franck Marie Leclère, Marcel Gregor Rees
    5 Apr 2014 | 2:22 am
    ABSTRACT Carpal tunnel syndrome is the most common entrapment neuropathy in the upper extremity. A rare case of carpal tunnel syndrome due to solitary osteochondroma arising from the metaphysis of the distal radius is presented. Preoperative diagnosis was suspected by physical examination and high-resolution sonography and confirmed by radiographs. Surgical treatment consisted of extended open carpal tunnel release and excision of the tumor. © 2014 Wiley Periodicals, Inc. J Clin Ultrasound, 2014
  • Thyroid tuberculosis mimics cancer on grayscale sonography and elastography

    Jian-hong Wang, Chun-ping Ning, Shi-bao Fang, Wei-wei Fu
    5 Apr 2014 | 2:22 am
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    Radiation Oncology - Latest Articles

  • Dosimetric advantages of a ¿butterfly¿ technique for intensity-modulated radiation therapy for young female patients with mediastinal Hodgkin¿s lymphoma

    Khinh Voong
    14 Apr 2014 | 5:00 pm
    Purpose: High cure rates for Hodgkin's lymphoma must be balanced with long-term treatment-related toxicity. Here we report an intensity-modulated radiation therapy (IMRT) technique that achieves adequate target coverage for mediastinal disease while minimizing high- and low-dose exposure of critical organs.Methods and materials: Treatment plans for IMRT and conventional anteroposterior-posteroanterior (AP-PA) techniques, with comparable coverage of the planning target volume (PTV), were generated for 9 female patients with mediastinal Hodgkin's lymphoma assuming use of inclined positioning,…
  • Influence of body mass index and periprostatic fat on rectal dosimetry in permanent seed prostate brachytherapy

    David Tiberi
    13 Apr 2014 | 5:00 pm
    Purpose: We examined the influence of body mass index (BMI) and body fat distribution on rectal dose in patients treated with permanent seed brachytherapy for localized prostate cancer.Methods and materials: We analyzed 213 patients treated with I125 seed brachytherapy for localized prostate cancer. BMI and rectal dosimetry data for all patients were available. Data on visceral and subcutaneous fat distribution at the level of the iliac crest (n = 140) as well as the distribution of periprostatic and subcutaneous fat at the symphysis pubis level were obtained (n = 117). Fat distribution was…
  • Radiation Oncology Reviewer Acknowledgement 2013

    Claus Belka
    3 Apr 2014 | 5:30 am
    Contributing reviewersThe editors of Radiation Oncology would like to thank all our reviewers who have contributed to the journal in Volume 8 (2013).
  • Effects of the dose-volume relationship on and risk factors for maxillary osteoradionecrosis after carbon ion radiotherapy

    Go Sasahara
    2 Apr 2014 | 5:00 pm
    Background: Osteoradionecrosis (ORN) is a critical complication after carbon ion (C-ion) or photon radiotherapy (RT) for head and neck tumors. However, the risk factors for ORN after C-ion RT remain unclear. Therefore, the present study aimed to investigate the effects of the dose-volume relationship on and risk factors for ORN development after C-ion RT. We, however, focused on the maxillary bone because most tumors treated with C-ion RT were primarily located in the sinonasal cavity. Methods: The patients enrolled in this study received more than 10% of the prescribed total dose of 57.6 Gy…
  • Stereotactic body radiotherapy (sbrt) in lung oligometastatic patients: role of local treatments

    Pierina Navarria
    1 Apr 2014 | 5:00 pm
    Background: Data in the literature suggest the existence of oligometastatic disease, a state in which metastases are limited in number and site. Different kinds of local therapies have been used for the treatment of limited metastases and in the recent years reports on the use of Stereotactic Ablative radiotherapy (SABR) are emerging and the early results on local control are promising.Patients and methods: From October 2010 to February 2012, 76 consecutive patients for 118 lung lesions were treated. SABR was performed in case of controlled primary tumor, long-term of progression disease,…
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    radiology « Tag Feed

  • MRI Improves Detection of Higher Risk Prostate Cancer

    26 Mar 2014 | 8:54 am
    Magnetic resonance imaging (MRI) andMRI-guided prostate biopsy can greatly reduce the detection of low-risk prostate tumors while increasing detection of intermediate- and high-risk tumors, according to the findings of a recent study. Leslie C. Thompson, MBBS, FRACS, a consultant urologist at The Wesley Hospital and Wesley Research Institute in Brisbane, Australia, and colleagues compared multiparametric MRI (mpMRI) followed by MRI-guided biopsy (MRGB) with transrectal ultrasound-guided biopsy (TRUSGB) in the detection of prostate cancer (PCa) in 223 biopsy-naïve men referred by urologists…
  • MRI Improves Detection of Higher Risk Prostate Cancer

    Dr Irwin Best
    26 Mar 2014 | 8:48 am
    Magnetic resonance imaging (MRI) andMRI-guided prostate biopsy can greatly reduce the detection of low-risk prostate tumors while increasing detection of intermediate- and high-risk tumors, according to the findings of a recent study. Leslie C. Thompson, MBBS, FRACS, a consultant urologist at The Wesley Hospital and Wesley Research Institute in Brisbane, Australia, and colleagues compared multiparametric MRI (mpMRI) followed by MRI-guided biopsy (MRGB) with transrectal ultrasound-guided biopsy (TRUSGB) in the detection of prostate cancer (PCa) in 223 biopsy-naïve men referred by urologists…
  • Top 5 Report Creation Annoyances in Radiology

    3M Health Information Systems
    26 Mar 2014 | 7:30 am
    It’s about productivity and accuracy – anything else is a distraction Guest blog by Dr. Arnold Raizo
  • How Much Do You Know About Breast Cancer Risk? (Answers)

    Diagnostic Imaging Centers, P.A.
    26 Mar 2014 | 6:42 am
    Now that you’ve taken our breast cancer risk survey… how well did you do? Here’s what we want you to know: Being a woman puts you at risk for breast cancer. Period. If you have breasts, you are at risk. Annual screening mammograms need to start at age 40. Family history increases risk for breast cancer. A lack of family history DOES NOT mean you are exempt – upwards of 80% of all breast cancer cases are diagnosed in individuals who have no family members who have had breast cancer. Having a lucky family doesn’t get you off scott-free. Compression per breast for a mammogram lasts…
  • Breast Cancer Risk Survey

    Diagnostic Imaging Centers, P.A.
    26 Mar 2014 | 6:41 am
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    The Radiology Portal

  • Web Browsers did you know, from site point

    Dave Woeber
    17 Apr 2014 | 3:32 pm
    Louis Lazaris Managing Editor SitePoint SitePoint Newsletter We all know that web browsers like Chrome, Firefox, and Internet Explorer are free to download and use, right? Leaving privacy and spying issues aside, while it is true that such software is free from a monetary perspective, the vendors producing the software are benefiting immensely. Here are some things you might not be aware of when it comes to browser software: Google pays browser vendors (like Mozilla) “search royalties” to include Google as the primary search engine on the browser. (source) In 2012 Mozilla had a…
  • Radiation Dose You Get When Holding the IR for a Swimmers Exposure

    Dave Woeber
    17 Apr 2014 | 3:16 pm
    This is a very important article for Radiographer’s and student’s. It was written by Dennis Bowman, radiographer at Community Hospital of the Monterey Peninsula. You can access this article here:  Radiation Dose You Get When Holding the IR for a Swimmers Exposure. Thank you Dennis for sharing this article.
  • CT in pregnant patient, From CTisus on Facebook

    Dave Woeber
    7 Feb 2014 | 5:42 am
    CT in pregnant patient This a very interesting case, see it on CTisus on facebook. Post by CTisus: Cutting edge information on body CT (Computed tomography).
  • News Details | Joint Commission

    Dave Woeber
    7 Feb 2014 | 4:52 am
    Joint Commission Announces New and Revised Diagnostic Imaging Standards Changes to be implemented in two phases beginning in July 2014 December 20, 2013 Read the report:   News Details | Joint Commission. Are you ready to comply with new radiation safety rules? By Neomi Mullens, contributing writer
  • Becoming a Radiologic Technologist: A Student’s Guide: from Choosing the Right School to Jump Starting Your Career

    Dave Woeber
    3 Feb 2014 | 1:19 pm
    Jeremy Enfinger RT(R) (Author) This book is intended be used as a resource for people interested in becoming a Radiologic Technologist. There are many aspects to researching schools, the health care job market, and keys to success within the field of radiology. There are also many pitfalls like non accredited institutions that claim to qualify students to be able to work in a hospital as an x-ray tech after completion of their program, but do not meet accreditation standards needed to acquire the necessary credentials. This guide will provide everything the potential x-ray student needs to…
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    Sumer's Radiology Blog

  • Closed Lip Schizencephaly- Teaching Video

    Sumer Sethi
    16 Apr 2014 | 8:53 pm
    Schizencephaly is a rare cortical malformation that manifests as a grey matter-lined cleft extending from the ependyma to the pia mater.  Here is a case report.From Sumer's Radiology Site -The Top Radiology Magazine. Teleradiology Providers at Mail us at
  • Ryles tube in Skull: Teaching video

    Sumer Sethi
    16 Apr 2014 | 8:51 pm
    Here is an interesting case of a rare complication in RTA.From Sumer's Radiology Site -The Top Radiology Magazine. Teleradiology Providers at Mail us at
  • Florbetapir (18F) AMYViD PET Scan

    Sumer Sethi
    15 Apr 2014 | 12:21 pm
     Florbetapir (18F) (trade name AMYViD; also known as florbetapir-fluorine-18 or 18F-AV-45) is a PET scanning radiopharmaceutical compound containing the radionuclide fluorine-18, in 2011 FDA approved as a diagnostic tool for Alzheimer's disease. Florbetapir, like Pittsburgh compound B (PiB), binds to beta-amyloid, but due to its use of fluorine-18 has a half-life of 110 minutes, in contrast to PiB's radioactive half life of 20 minutes. Wong et al. found that the longer life allowed the tracer to accumulate significantly more in the brains of people with AD, particularly in the regions…
  • What do hotels and hospitals have in common?

    Sumer Sethi
    11 Apr 2014 | 2:36 am
    According to a recent article in Surgical Neurology International, there are a number of key ways that hospitals can drive patient care improvements by borrowing best practices from the hotel industry. According to the article, Despite widely divergent public perceptions and goals, hotels and hospitals share many core characteristics. Both serve demanding and increasingly well-informed clienteles, both employ a large hierarchy of workers with varying levels of responsibility, and both have payments that are increasingly tied to customer/patient evaluations. From Sumer's Radiology…
  • NY Times Reports: We Are Giving Ourselves Cancer

    Sumer Sethi
    11 Apr 2014 | 2:07 am
    The use of medical imaging with high-dose radiation — CT scans in particular — has soared in the last 20 years.  According to the article, While it is difficult to know how many cancers will result from medical imaging, a 2009 study from the National Cancer Institute estimates that CT scans conducted in 2007 will cause a projected 29,000 excess cancer cases and 14,500 excess deaths over the lifetime of those exposed. Given the many scans performed over the last several years, a reasonable estimate of excess lifetime cancers would be in the hundreds of thousands. According to our…
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    Topics in Radiography

  • Radiologic Technologist Job Hunt

    29 Mar 2014 | 10:04 am
    Today I went to Twitter and posted a slew of jobs I found in the San Diego area.  I know my fans aren’t all from around here, so I thought I would start a weekly regional job hunt covering a different region every Saturday morning from 7:00 a.m. to approximately 9:00 a.m. (or until I […]
  • #FreeJustina

    25 Mar 2014 | 11:32 am
    About 14 months ago at Boston Children’s Hospital, a teen named Justina Pelletier was removed from her parents’ custody and was moved from a traditional hospital room to a psychiatric ward.  The parents were accused of “medical child abuse”, or harming a child by pushing for unnecessary medical treatments.  She was initially brought to Boston Children’s for […]
  • An Open Letter to the California Radiation Health Branch

    13 Mar 2014 | 8:11 pm
    Dear California Radiation Health Branch, I did some research yesterday on your website about the requirements for renewing my CA x-ray license and fluoroscopy permit, and found a couple of new requirements I was previously unaware of.  Thank goodness I happened upon this because I’m not due until September to renew and submit my continuing […]
  • Fukushima Fallout: Why is there no Awareness?

    9 Feb 2014 | 9:40 am
    When the nuclear power plant began to melt down in Fukushima after the devastating tsunami swept through the Japanese coast line, the US was there to provide relief efforts, as we should be.  But after initial assessments of the safety of the fallout zone provided by the Japanese government (according to the video below), it […]
  • Custom X-Ray Marker Giveaway!

    20 Dec 2013 | 9:30 pm
    a Rafflecopter giveaway To enter for your chance to win a free set of x-ray markers from Karmamarkers, simply do one or more of the following: Tweet about the giveaway (one entry per day) Like Karmamarkers on Facebook (one time only) Like Topics in Radiography on Facebook (one time only) Follow @Karmamarkers on Twitter (one […]
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    Ultrasound Technician Center

  • Accredited Ultrasound Technician Schools in Charleston SC or Nearby

    Lisa Parmley
    18 Apr 2014 | 12:31 am
    As one of the oldest cities in the U.S., Charleston is known for its charm, architectural beauty, and historical significance. The area residents spend a lot of time outdoors because of the mild climate and the accessibility of the mountains, five beaches, and numerous biking and walking trails that include city and country paths. In […]
  • Best 4 Accredited Ultrasound Technician Schools in San Jose CA and Nearby

    Lisa Parmley
    16 Apr 2014 | 11:31 pm
    San Jose, California has the Diablo Mountain range to the east and the Santa Cruz Mountains to the west. The city has a mild climate, making it an ideal locale for healthy outdoor lifestyles. Recreational areas include Kelley Park and Alum Rock Park. This is an excellent choice of cities for Diagnostic Medical Sonography students […]
  • 6 Accredited Ultrasound Technician Schools in Tulsa OK and Nearby

    Lisa Parmley
    16 Apr 2014 | 12:24 am
    Tulsa, Oklahoma is said to be in the “Green Country” because it has rolling hills and many wooded areas. It has been named as one of “America’s Most Livable Communities.” Anyone studying sonography or working as an ultrasound technician will find a rich variety of arts inside museums and outside in the numerous recreational areas […]
  • Top 100+ Accredited Ultrasound Technician Certificate Programs in 2014

    Lisa Parmley
    15 Apr 2014 | 12:56 am
    The sonography certificate programs train students who want to gain the knowledge and skills needed to work as a Diagnostic Medical Sonographer or an ultrasound technician. Students entering ultrasound technician certificate programs today frequently have already earned an Allied Health degree or a degree in another discipline and want to upgrade and expand skills. Sonographers […]
  • Best 6 Accredited Ultrasound Technician Schools in Ontario CA and Nearby

    Lisa Parmley
    14 Apr 2014 | 1:49 am
    The city of Ontario is in San Bernardino County and approximately 35 miles from Los Angeles. Ultrasound technicians have a wide range of employment options since there is easy access to healthcare facilities on a regional basis. When not studying or working, residents enjoy the Southern California lifestyle by taking advantage of outdoor activities like […]
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